The Donald S. Fredrickson Papers Donald Fredrickson (1924-2002) was an American physiologist and biomedical research leader who made significant contributions to medicine over the course of four decades. Fredrickson's system of classification of abnormalities in fat transport was adopted by the World Health Organization as an international standard for identifying increased risks of coronary artery disease linked to the consumption of fats and cholesterol. He also discovered two genetic diseases caused by disorders in lipid metabolism. As director of the National Institutes of Health (NIH), Fredrickson mediated between scientists and the federal government during debates over the direction of medical research policy, funding, and the dangers of genetic engineering during the second half of the 1970s. The National Library of Medicine is the repository for the Donald S. Fredrickson Papers, which range from 1910 to 2002. The collection contains research reports, published articles and books, poems, correspondence, unpublished manuscripts, speeches, news clippings, photographic prints, and audiovisual materials. As part of its Profiles in Science project, the National Library of Medicine is digitizing and making available over the World Wide Web a selection of the Donald S. Fredrickson Papers, for use by educators and researchers. This Web site provides access to the portions of the Donald S. Fredrickson Papers that are now publicly available. Individuals interested in conducting research in the Donald S. Fredrickson Papers are invited to contact the National Library of Medicine. This online Exhibit is designed to introduce you to the various phases of Fredrickson's scientific career and professional life. It is divided into sections that focus on Fredrickson's life and major scientific contributions. We suggest that new visitors begin with this exhibit, which includes a small selection of documents and visuals, organized within these sections. Each section begins with a "Background Narrative," which leads to "Documents" and "Visuals." Visitors may access additional materials through Search on the navigation bar. They may also view the materials alphabetically or chronologically by choosing Browse on the navigation bar. Documents and visuals in these lists are arranged by format and then either alphabetically by title or chronologically.